‘Geno 2.0: Next Generation’ Reveals New Details of Your Ancient Ancestry

Geno 2.0: Next Generation (Geno NextGen) is the next phase of the Genographic Project, National Geographic’s pioneering effort to decode the story of individuals’ deep ancestry hidden within their DNA. Geno NextGen builds on the success of Geno 2.0 by growing the analytical capabilities of the test and enhancing the participant Geno 2.0 experience.

Geno NextGen. Image courtesy of National Geographic

Here are the new and enhanced features of Geno NextGen:

We are including thousands of new Y chromosome and mitochondrial DNA mutations, allowing for the highest resolution in maternal and paternal haplogroup (family clan) assignment, shy of genome or chromosomal sequencing. The new mutations will allow for dozens of new haplogroup stories.

New Genographic Chip, courtesy of Ilumina, Inc.
New Genographic Chip. Image courtesy of Ilumina, Inc.

Regional affiliations will now be estimated from eighteen populations. By analyzing more than 700,000 mutational markers across the entire human genome—an increase from the 150,000 used in Geno 2.0—researchers can now estimate the geographical components of your DNA from double the number of regional affiliations and then compare these results to more than 50 reference populations. Participants can learn if they are similar to people from Ireland, Germany, Lebanon, or maybe all of the above.

Sample of results. Image from www.genographic.com
Sample results. Image from www.genographic.com

We are recalculating the Neanderthal DNA percentage with higher precision. In the last three years, we have learned much more about who Neanderthals were and how they interacted with our ancestors, and we are incorporating what we learned into the new experience with a recalculation of participant’s Neanderthal DNA.

Next Gen participants looking for genealogical matches can now easily transfer results to our laboratory partners at Family Tree DNA and search for relatives across their large database.

As a continued promise to all participants, the Genographic Project will not test for or report on any medical markers and will never sell DNA results. To learn more about the Genographic Project or how to get a Geno NextGen kit visit us at www.genographic.com.

Changing Planet

Meet the Author
Dr. Miguel Vilar is the Science Manager for National Geographic's Genographic Project. Miguel is also a molecular anthropologist and a science writer. His fieldwork has taken him to remote places throughout the South Pacific, East Africa, Mesoamerica, and the Caribbean. In the laboratory he researches the modern genetic diversity of human populations from Melanesia, Micronesia, North and Central America, and the Caribbean. Miguel has published in several anthropology and genetics journals, as well as popular science magazines.